Archive

A phase 2a randomised, double-blind, placebo-controlled, parallel-group, add-on clinical trial of ebselen (SPI-1005) as a novel treatment for mania or hypomania.

Contributors: Cowen, Philip J; Godlewska, Beata R; Holder, Adele A; Macdonald, Orla; Sharpley, Ann L; Williams, Clare

Subjects: Bipolar Disorder, Hypomania, Mania

Translating the promise of 5HT4 receptor agonists for the treatment of depression

Contributors: Cowen, Philip J; De Cates, Angharad N; Gillespie, Amy L; Godlewska, Beata R; Harmer, Catherine J; Murphy, Susannah E; Scaife, Jessica; Wright, Lucy C

Subjects: Cognition, Depressive Disorders

Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis

Contributors: Cipriani, Andrea; Cowen, Philip J; De Crescenzo, Franco; Efthimiou, Orestis; Kurtulmus, Ayse; Ostinelli, Edoardo; Quested, Digby J; Tomlinson, Anneka

Subjects: Insomnia

An online experimental medicine trial on the effect of 28-day simvastatin administration on emotional processing, reward learning, working memory and salivary cortisol in healthy volunteers at risk for depression: OxSTEP protocol

Contributors: Cowen, Philip J; Di Giorgi, Riccardo

Subjects: Depressive Disorders, Inflammation

A leaky umbrella has little value: evidence clearly indicates the serotonin system is implicated in depression

Contributors: Browning, Michael; Cowen, Philip J; Goodwin, Guy M; McCutcheon, Robert A

Subjects: Depressive Disorders

Fifty years on: Serotonin and depression

Contributors: Browning, Michael; Cowen, Philip J

Subjects: Antidepressant Drugs, Depressive Disorders

Acute neural effects of fluoxetine on emotional regulation in depressed adolescents

Contributors: Capitao, Liliana; Chapman, Robert; Cowen, Philip J; Harmer, Catherine J; James, Anthony; Murphy, Susannah E; Wright, Lucy C

Subjects: Adolescents and Young Adults, Depressive Disorders

Déjà-vu? Neural and behavioural effects of the 5-HT 4 receptor agonist, prucalopride, in a hippocampal-dependent memory task

Contributors: Cowen, Philip J; De Cates, Angharad N; Gibson, Daisy; Harmer, Catherine J; Murphy, Susannah E; Wright, Lucy C

Subjects: Cognition

Statins in depression: a repurposed medical treatment can provide novel insights in mental health

Contributors: Cowen, Philip J; De Giorgi, Riccardo; Harmer, Catherine J

Subjects: Antidepressant Drugs, Depressive Disorders

Adaptive learning from outcome contingencies in eating-disorder risk groups

Contributors: Browning, Michael; Cowen, Philip J; Park, Rebecca J; Pike, Alexandra C; Pulcu, Erdem; Sharpley, Ann L

Subjects: Eating Disorders