Abstract

The molecular underpinnings of psychiatric disorders remain elusive despite there being a paramount need to establish druggable targets for their treatment.

Genome-wide association studies (GWASs) have identified numerous candidate genes implicated in the pathology of psychiatric disorders.

However, a key challenge is to identify time intervals when implicated biological pathways are germane.

This information is critical from a drug development perspective because it guides when psychopharmacotherapy should be applied to achieve maximum effect.

Citations

Noura Al-Jouffali. Critical Developmental Windows of Voltage-Gated Cation Channel Expression in Psychiatric Disorders. Biological Psychiatry. VOLUME 90, ISSUE 6, E31-E32, SEPTEMBER 15, 2021

DOI: https://doi.org/10.1016/j.biopsych.2021.07.005

URI: https://www.oxfordhealth.nhs.uk/orka/title/critical-developmental-windows-of-voltage-gated-cation-channel-expression-in-psychiatric-disorders/