Abstract

Stroke survivors are routinely screened for cognitive impairment with tools that often fail to detect subtle impairments.

The Oxford Cognitive Screen-Plus (OCS-Plus) is a brief tablet-based screen designed to detect subtle post-stroke cognitive impairments.

We examined its psychometric properties in two stroke cohorts (subacute: <3 months post-stroke, chronic: >6 months post-stroke).

Patients and Methods This study included 347 stroke survivors (mean age = 73 years; mean education = 13 years; 43.06% female presenting; 74.42% ischaemic stroke).

The OCS-Plus was completed by 181 sub-acute stroke survivors and 166 chronic stroke survivors.

All participants also completed the Oxford Cognitive Screen (OCS) and a subset completed the Montreal Cognitive Assessment (MoCA) and further neuropsychological tests.

Results

First, convergent construct validity of all OCS-Plus tasks against task-matched standardized neuropsychological tests was confirmed.

Second, we evaluated divergent construct validity of all OCS-Plus subtasks.

Third, we report the sensitivity and specificity of each OCS-Plus subtask compared to neuropsychological test performance.

Fourth, we found that OCS-Plus detected cognitive impairments in a large proportion of those classed as unimpaired on MoCA and OCS.

Discussion and Conclusion The OCS-Plus provides a valid screening tool for sensitive detection of subtle cognitive impairment in stroke patients.

Indeed, the OCS-Plus detected subtle cognitive impairment at a similar level to validated neuropsychological assessments and exceeded detection of cognitive impairment compared to standard clinical screening tools.

Citations

Sam S Webb, Georgina Hobden, Rebecca Roberts, Evangeline G Chiu, Sarah King, and Nele Demeyere.Validation of the UK English Oxford Cognitive Screen-Plus in Sub-Acute and Chronic Stroke Survivors.PsyArXiv. June 9

DOI: https://doi.org/10.31234/osf.io/y8we5

URI: https://www.oxfordhealth.nhs.uk/orka/title/validation-of-the-uk-english-oxford-cognitive-screen-plus-in-sub-acute-and-chronic-stroke-survivors/